Documents for ICFP M2 lecture set "Statistical Biophysics "

First lecture. An introduction to molecular biology and its modelling

• Slides

• Miller's experiment (1953)

• Meselson and Stahl's experiment (1958)

2nd lecture. Regulation of Transcription, small networks, ...

• Slides

3rd lecture. Fluctuations ("noise") in gene/protein networks

• Slides

4th lecture. Some bits on evolution and population genetics

• Slides

5th lecture. Physical limits to information processing

• Slides

6th lecture. Different ways to create patterns : Turing vs Morphogen gradients and positional information

• Slides Turing.

• Slides positional information.

• Turing's classic paper (1952)

• Another very influential paper : Gierer and Meinhardt (1972)

• A review of biological examples of Turing's mechanism : Kondo and Miura, Science (2010) , and recent progresses in mechanistic description Hamada et al, Development (2014)

• An interesting and well-documented example of localized state a la Gierer-Meinhardt in left-right asymmetry
A short review : Tabin, Cell (2006) , Measurement of diffusion constants : Mueller et al, Science (2012) with a short overview Hamada, science (2012)

• A short review on cell polarity and localized states : Johnson and Dew (2009)

Lecture. Inference and applications to Biology (S. Cocco and R. Monasson).

• Slides I ,
• Slides II

Last lecture. Cell motion

• Slides

HW3 2nd problem : PG de Gennes' paper.

• paper